Website is intended for physicians
Search:

Abstract

Background: in patients with congestive heart failure (CHF), there is a change in indicators of heart mechanics against the background of myocardium remodeling. Currently, magnetic resonance imaging (MRI) and speckle tracking echocardiography provide additional options for assessing changes in heart mechanics. Evaluation of mechanics of the myocardium rotational movement according to coronarography (CAG) has not been found in available literature. In this regard, there is a need to develop a methodology that allows to obtain a mathematical description of rotation processes and heartbeat during the CAG.

Material and methods: study included 90 patients aged 30-71 to assess indicators of heart rotation mechanics. Subjects were divided into groups: with dilated cardiomyopathy (DCMP, n=30), left ventricular aneurysm (LVA, n=30) and patients with autonomic nervous system disorder (ANSD, n=30) without heart failure (control group). Mechanics of heart rotation was studied using the CAG technique, modified by us, based on mathematical calculations of the rotation angle in motion of points on the heart surface, determined on the coronary angiogram in two projections.

Results: study found out, that in patients with DCMP and LVA with chronic heart failure, the angle of rotation of the heart was significantly lower than in patients with ANSD who do not have heart disease (p <0,05). The link between impaired myocardial contractile function in patients with DCMP and LVA with chronic heart failure and a decrease in the heart rotation angle was confirmed (DCMP: ?2=9,774; df=1; P <0,05), (LVA: ?2=9,600; df=1; P <0,05).

Conclusion: coronarography technique that we modified, makes it possible to quantify changes in parameters of the heart mechanics in examined patients. This makes it possible to determine the presence or absence of heart failure, depending on results.

  

References 

1.     Fomin IV. Chronic heart failure in the Russian Federation: what we know today and what we should do. Russian Journal of Cardiology. 2016, 8(136): 7-13 [In Russ].

2.     Belenkov YuN, Mareev VYu. Principles of rational treatment of heart failure.M. 2000. 266 [In Russ].

3.     Popescu BA, Beladan CC, Calin A, et al. Left ventricular remodelling and torsional dynamics in dilated cardiomyopathy: reversed apical rotation as a marker of disease severity. EurJHeartFail. 2009;11(10): 945-51.

4.     Pavlyukova EN, Kuzhel' DA, Matyushin GV, Savchenko EA, Filippova SA. Rotation, twisting and spinning of the left ventricle: physiological role and significance in clinical practice. Regional pharmacotherapy in cardiology. 2015; 11(1): 68-78 [In Russ].

5.     Mondillo S, Galderisi M, Mele D, et al.; Echocardiography Study Group Of The Italian Society Of Cardiology (Rome, Italy). Speckle-tracking echocardiography: a new technique for assessing myocardial function. J Ultrasound Med. 2011;30(1):71-83.

6.     Sergio Mondillo, MD, Maurizio Galderis, et al. Speckle-tracking echocardiography - a technique for assessing myocardial function. June 2, 2016. The international online community of specialists in ultrasound diagnostics [In Russ].

7.     Leitman M, Lysyansky P, Sidenko S et al. Two-dimensionalstrain - a novel software for real-time quantitative echocardiographic assessment of myocardial function. J. Am. Soc. Echocardiogr. 2004; 17(10): 1021-1029.

8.     Amundsen BH, Helle-Valle T, Edvardsen T et al. Noninvasive myocardial strain measurement by speckle tracking echocardiography: validation against sonomicrometry and tagged magnetic resonance imaging. J. Am. Coll. Cardiol. 2006; 47(4): 789-793.

9.     Buckberg G.D., Weisfeldt M.L., Ballester M. [et al.] Left ventricular form and function: scientific priorities and strategic planning for development of new views of disease. Circulation. 2004; 110: 333-336.

10.   Mirsky I., Parmley W.W. Assessment of passive elastic stiffness for isolated heart muscle and the intact heart. Circ. Res. 1973; 33: 233-243.

11.   Pouleur A., Knappe D., Shah A. [et al.] Relationship between improvement in left ventricular dyssynchrony and contractile function and clinical outcome with cardiac resynchronization therapy: the MADIT-CRT trial. Eur. Heart J. 2011; 32:1720-29.

12.   Vermes E., Tardif J.C., Bourassa M.G. [et al.] Enalapril decreases the incidence of atrial fibrillation in patients with left ventricular dysfunction: insight from the Studies of Left Ventricular Dysfunction (SOLVD) trials. Circulation. 2003; 931: 2926-2.

13.   Victor Mor-Avi et al. The consensus decision of the American Echocardiographic Society and the European Association of Echocardiography on the methodology and indications, approved by the Japanese Society of Echocardiography. Articles. 07/07/2015 [In Russ].

14.   Roberto M Lang, Michelle Bierig [et al.] Roberto M Lang, Michelle Bierig [et al.]Recommendations for quantifying the structure and chambers of the heart.. Russian Journal of Cardiology 2012; 3(95). This edition of guidelines is published in Eur J Echocardiography 2006; 7: 79-108 [In Russ].

ANGIOLOGIA.ru (АНГИОЛОГИЯ.ру) - портал о диагностике и лечении заболеваний сосудистой системы